KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASR
All Species:
18.18
Human Site:
S169
Identified Species:
50
UniProt:
P41180
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41180
NP_000379.2
1078
120674
S169
I
P
Q
V
S
Y
A
S
S
S
R
L
L
S
N
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY96
1079
120821
S169
I
P
Q
V
S
Y
A
S
S
S
R
L
L
S
N
Rat
Rattus norvegicus
P48442
1079
120849
S169
I
P
Q
V
S
Y
A
S
S
S
R
L
L
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515899
1088
120096
S169
I
P
Q
V
S
Y
A
S
S
S
R
L
L
S
N
Chicken
Gallus gallus
XP_416491
1059
118051
S169
I
P
Q
V
S
Y
A
S
S
S
R
L
L
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
N112
S
R
D
T
Y
A
L
N
Q
S
L
Q
F
V
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
25.7
N.A.
N.A.
93.6
93.6
N.A.
81.9
85.4
N.A.
30.6
N.A.
26.8
N.A.
N.A.
N.A.
Protein Similarity:
100
43.5
43.4
N.A.
N.A.
96.8
96.9
N.A.
87.8
90.5
N.A.
47.5
N.A.
46.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
N.A.
N.A.
100
100
N.A.
100
100
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
0
N.A.
N.A.
100
100
N.A.
100
100
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
56
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
56
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
12
0
0
0
12
56
56
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
56
% N
% Pro:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
56
0
0
0
0
0
12
0
0
12
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
56
0
0
0
12
% R
% Ser:
12
0
0
0
56
0
0
56
56
67
0
0
0
56
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
56
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
56
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _